The search for a drug against obesity seems to be successful. So-called incretin mimetics increase the feeling of satiety and make it easier to lose weight. And with the drug semaglutide, test subjects lost an average of 15 percent body weight. Of course, it is important to first try everything to lose weight and feel good without medication. Exercise and a healthy diet are particularly important. Natural vital substances can also help.

It was frightening news in mid-February: in England and Scotland, more people have died in recent years from the consequences of being overweight than from the effects of smoking. That's according to a new study from Glasgow. Between 2013 and 2017, smoking-related deaths in the countries fell by almost four percentage points to 19 per cent, while those related to obesity increased by more than five percentage points to just over 23 per cent, according to the study. According to official figures, almost two thirds of citizens in Great Britain are too fat. We also have this problem in Germany. Two-thirds of men and half of women are overweight, and a quarter of adults are even severely overweight, i.e. obese.

One problem is that there is still no effective medicine against obesity. But now the tide may be turning, writes the "Neue Zürcher Zeitung" in the article "The search for a drug against obesity seems to be successful": "There are increasing indications that a new group of drugs can make the superfluous fat deposits disappear more sustainably than all previous ones - and benefit health in other areas as well.

Incretin mimetics increase the feeling of satiety and facilitate weight loss

We are talking about synthetic intestinal hormones, so-called incretin mimetics. Incretin mimetics are blood sugar-lowering drugs used in the treatment of people with type 2 diabetes. "Incretin mimetics increase the release of insulin depending on the amount of carbohydrate ingested and delay gastric emptying. This lowers the blood sugar level. Especially the blood sugar peaks after eating decrease. The risk of hypoglycaemia and nocturnal hypoglycaemia is lower than with insulin therapy. In addition, incretin mimetics increase the feeling of satiety and make it easier to lose weight. Animal studies have also shown that these active substances prevent the death of beta cells and improve the function of the insulin-producing cells of the pancreas," says the specialist portal Vitanet.de.

Certain messenger substances control sugar balance and food intake

The Neue Zürcher Zeitung writes: "Like their natural role models, the incretins, they steer the blood sugar into regulated channels and also control the appetite. The fact that the same messenger substances control both the sugar balance and food intake shows how closely these two parameters are linked. It is therefore no coincidence that obesity is the most important driver of so-called old-age diabetes and, conversely, that losing excess pounds is the best way to counteract diabetes and its consequences."

Another drug, semaglutide, has also been shown in a new study to be an extremely potent means of combating obesity. According to the Neue Zürcher Zeitung, about 2000 middle-aged people who weighed an average of 105 kilograms and did not suffer from diabetes took part in the study. In addition to intensive lifestyle counselling, two thirds of the test persons had been treated with semaglutide for a good year and the remaining third with a placebo. According to the scientific journal "New England Journal of Medicine", the test subjects in the semaglutide group lost an average of 15 kilograms, i.e. 15 percent of their initial weight. In contrast, those in the placebo group lost an average of only 2.5 kilograms. The former also felt better all round and less physically restricted than the latter.

WHO recommends one hour of exercise per day

This is good news for people who suffer from morbid obesity. But of course it is important to first try everything to lose weight and feel good without medication. Exercise and a healthy diet are particularly important. The World Health Organisation (WHO) recommends that people get one hour of exercise a day. This includes walking to the bakery and taking the stairs instead of the lift. That is a good start. If you want to exercise more intensively, you need an individually tailored exercise programme, preferably in consultation with your doctor.

Natural vital substances also offer further support. Natura Vitalis has developed the innovative metabolism cure "IQ28". Besides protein and amino acids, sufficient vitamins and minerals play an extremely important role for a well-functioning metabolism. These substances are contained in "IQ28". This in turn leads to a 24-hour fat burning process. In the natural metabolic state, the stored fats are released and converted in the liver into so-called ketones, which are used instead of carbohydrates for all cells to produce energy.

Meanwhile, it is also known that L-carnitine plays an important role in the energy metabolism in humans and animals as well as in plant cells. This means that a person with a fast metabolism burns off a lot of the energy that he or she has taken in through food. This therefore accelerates weight loss through exercise, dieting and dietary changes.

Change your eating habits in the long term

Balance also applies to nutrition. Plenty of fruit and vegetables, little fat and sugar, and at the same time about two litres of water a day - that will lead you to your goal in the long run. If you really want to lose weight, you cannot avoid changing your eating habits in the long term. Equally important: a sufficient supply of healthy, natural vital substances. These include protein and the amino acids it contains. They help you reach your desired weight and then maintain it. Because protein makes you feel fuller for longer, and your body needs calories to burn it off. Most importantly, protein also prevents you from losing muscle instead of fat when you lose weight. CLA, a natural polyunsaturated fatty acid, also helps eliminate belly fat quickly. CLA boosts fat burning, reduces fat absorption from food and lowers levels of the protein leptin, which causes weight gain. Vitamin C also contributes to normal energy metabolism. Magnesium, zinc, chromium, iodine and also biological substances such as green coffee have also proven to be great weight loss supporters.

This text may contain translation errors as the translation was done by an online translation tool.